The frequent occurrence of seismic events poses significant challenges to structural integrity, particularly in regions with high tectonic activity. This research aims to explore advanced computational techniques to enhance the structural resilience of buildings in seismic zones. Utilizing finite element analysis and dynamic response simulations, we assessed the impact of varying seismic intensities on both traditional and modern building materials. Our methodology included a detailed simulation of seismic forces and stress distribution across different structural configurations. The findings reveal that innovative computational models, combined with seismic-resistant materials, can significantly enhance the durability and safety of structures. Furthermore, the study highlights the potential benefits of integrating adaptive damping systems in high-risk areas. This research underscores the importance of adopting cutting-edge engineering techniques to mitigate the risks associated with seismic activities. The enhanced structural models developed could be vital for engineers and policymakers in designing safer infrastructures. Our conclusions advocate for the adoption of these computational approaches in the standard practices of engineering design to improve resilience and reduce the risk of structural failures in seismic-prone regions.