๐Ÿ“ Abstract

Introduction: Study was performed on patients to whom total intravenous anesthesia (TIVA) was performed with target controlled infusion method (TCI) in endovenous laser ablation surgery (EVLA). The purpose of the study was to evaluate the effects of propofol and remifentanyl added propofol on LMA insertion and total drug doses during the maintenance of anesthesia, hemodynamic parameters, side effects during pre and post operative periods, additional analgesic requirements and discharge criteria.\n Materials and Method: The Retrospective study was performed with the consent of Ankara Numune Training and Research Hospital Scientific Research Evaluation Committee. Patients who had TIVA with TCI method in the EVLA surgery were included to the study. Patients over the age of 65, with ASA 3-4, body mass index over 40 kg/mยฒ and patients to whom different anesthesia methods and drugs were administered were excluded from the study. Group I (n=30) was started with remifentanyl with 2 ng/ml effect site target concentration. When effect site target concentration was reached propofol was added to reach 3ยตg/ml effect site target concentration. Group II (n=30) was started to propofol infusion with 5ยตg/ml effect site target concentration. Hemodynamic parameters and BIS values were recorded pre-induction and post-induction at 5th, 10th, 15th, 20th, 25th, 30th and 60th minutes. LMA insertion and total drug doses during maintenance, side effects, additional analgesic requirements and discharge criteria were recorded.\nFindings: No intra group difference were detected in demographic values (p>0.05). Propofol dose used during LMA insertion was higher in Group II (p<0.05). Heart rate, induction at the 10th and 60th minutes and diastolic artery pressure measured at the 15th minute were different between groups (p<0.05). Mean artery pressure; was different in group I and II during induction, post induction at the 5th, 10th, 15th and 20th minutes when compared with the pre-operative value ( p<0.05). Peroperative additional analgesic requirement and bradycardia in post-operative period were high in Group II (p<0.05). \nDiscussion and results: It was observed that anesthetic depth and stability in the parameters was achieved and post-operative bradycardia was decreased by adding 2ng/ml effect site target concentration of remifentanyl to propofol during TCI application since it decreased propofol dose used during surgery and LMA insertion.

๐Ÿท๏ธ Keywords

PropofolRemifentanylTotal intravenous anesthesiatarget controlled infusionEVLA
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Citation

Ozge CIHANGIR OZEK, Ali Umit YENER, Belgin AKAN, Cihan KAPAN, Gizem OLGAC CICEK, Deniz ERDEM, Bayezit DIKMEN, Nermin GOGUS. (2021). COMPARISONS OF EFFECTS OF PROPOFOL AND REMIFENTANYL ADDED PROPOFOL IN TARGET CONTROLLED INFUSION METHOD IN ENDOVENOUS LASER ABLATION SURGERY. Cithara Journal, 61(3). ISSN: 0009-7527