This review aims at comprehensively reporting the impact of Salmonellosis in humans of developing Asian countries, the mode of dissemination, the various methods of serotyping, drug-resistance and the distribution of different Salmonella serotypes in these countries. The review focusses mainly on developing Asian countries which have a big population, higher risk of dissemination of the pathogen due to poor standards of public hygiene and sanitation, and also a high rate of arriving and departing travellers. Moreover, most of these countries lack a proper continuous surveillance and control system to monitor the epizootiology of Salmonella serovars.\nVarious serotypes that were prevalent in Asian countries included the following: S. weltevreden, S. rissen and S. typhimurium, S. anatum, S. rissen, S. stanley and S. enteritidis. A high degree of serotypes distribution was found among the different countries. Resistance to multiple drugs was present in many serovars. The reported results indicate an alarming rate of human Salmonellosis in developing Asian countries, highlighting the importance of developing stringent surveillance and control programs aiming at control of this pathogen.