PVY and PLRV disease is widespread wherever potato is grown. Yield losses due to these viral diseases are up to 83% in Pakistan. Plant extracts i.e. Neem, Ginger, Garlic, Akk, Ginger, Dature and Thuja including an untreated check with three replication and each replication had three dose levels were sprayed @ 3, 5 and 8gm/L on the variety desiree which was grown in RCBD trial and sprayed 1 time only. ELISA absorbance reading showed that non of the plant extract had significant role to control the multiplication of PVY virus concentration inside the plants but the alcoholic extract of Thuja had a significant effect on PLRV multiplication within the leaves of plants . The absorbance reading of ELISA reactions at 405 nm was found to be maximum 1.356 (25 days after spray @) 8gm/L) compared with control i.e. 3.982. Aphis gossypii was the most abundant, while M. persicae was the least abundant. Thuja orientalis (Thuja) was found to be the most effective to minimize the population of aphids (Macrosiphum euphorbiae; Myzus persicae; Aphis gossypii) as compared to the other treatments.