The current research is aimed to identify the role of entrepreneurship education in economic empowering of rural women cooperatives in Shiraz city. The population of this research include the members of the women cooperatives in Shiraz city (N= 1151). By using proportional stratified sampling 300 people were selected according to Morgan table. The data of the study is collected by a questionnaire. The findings showed that there is a positive relationship between the economic empowering and achievement motivation aspects, venturing, creativeness, self-sufficiency, and internal control in the level of 99 percent. Also the results of regression analysis indicated that creativeness has determined 0.46 variance of economic empowerment of rural women cooperatives in Shiraz Township