Background: Multiple Sclerosis (MS) is a neurodegenerative autoimmune demyelinating disease affecting young adults. Possible abnormalities of serum or plasma components in patients with multiple sclerosis have attracted the attention of many investigators \nResearch question: The purpose of this study was to investigate the effect of aerobic dancing training on serum lipid profile in women with RRMS to assess if aerobic exercise group exhibit improvements in lipid profile compared to control group. \nType of study: Randomized controlled study. \nMethods: Twenty eight RRMS patients (age: 35.14±6.37 years; height: 163.0±6.65cm; weight: 68.62±12.31kg;Body mass index:25.75±3.89 kg/m-2 )with mild disability (EDSS≤ 3) participated in this study. The subjects were divided into two groups, exercise group (n=15) and control group (n=13). Exercise Group participated in aerobic dancing training program at 50 -70 % HRR for 8 weeks and 3 sessions per week. Exercises performed in the study included of aerobic dancing training program.\n Triglyceride (TG), cholesterol (TC), high density lipoproteins (HDL), low density lipoproteins (LDL) and very low density lipoproteins (VLDL) were measured before and after 8 weeks. \nResults: At the end of the 8 week period, significant decreases have been found in TG, TC and VLDL levels in exercise group(P<0.05).While there were no significant changes for the investigated factors in control group (P>0.05). \nConclusions: The results confirm a regular aerobic exercise cause favorable changes in lipids and lipoproteins in women patients with MS. In general, aerobic exercise is effective intervention for the management MS complications.