This study was, thus aimed at knowing the bait consumption acceptance (crushed maize) of rodents with the addition of natural Materials, seeds powder of cumin (Cuminum cyminum); coriander (Coriander sativum); anise (Pimpinella anisum ) and yeast as attractants and powders of black pepper seed (Piper nigrum); jeojoba seed (Simmondsia chinensis); oshar leaf, (Calotropis procera) and neem leaf (Azadirachta indica) as repellent under laboratory condition to reduce the rodent infestation crop. The results show that, the mean consumption of attractive baits was recorded, Yeast with crush maize (7.25 gm/rat) and coriander (2.35 gm/rat) are the most effective baits as compare with control treatment of (crush maize) only (0.9 gm/rat), fo r Rattus rattus frugivorus. But in Rattus rattus alexandrinus, it was observed that the mean consumption was high in yeast bait with crush maize (7.35 gm/rat), and anise (3.63 gm) as compare with control (2gm/rat).In Arvicanthis niloticus the mean consumption was high in yeast bait (4.75 gm) as compared with the control bait (1.83gm/rat). Baits preference tests should be done periodically to find out the proper bait for rodenticide formulation and to overcome the shyness of rodent baits. The mean consumption of repellent bait was less in black pepper bait with crush maize (0.32.5 gm/rat), jejoba seed (1.15 gm) as compared with control one (10.83gm/rat) for R.r.frugivorus. In R.r.alexandrinus was observed that the consumption was less in black pepper bait (0.38 gm/rat), and oshar leaf (0.85 gm/rat) as compared with control (7.05gm/rat). A. niloticus consumed scarce amount of black pepper bait (0.83 gm/rat) and leaf of oshar (1.58 gm/rat) as compared with control (7.9gm/rat) .Generally; these results may be satisfied in rodent control.