Table of Contents

Research Articles

1

Evaluating Efficacy and Safety of Novel Antiviral Agents in Acute Hepatitis C: A Multinational Trial

Thijs van der Meer, Zubaida Al-Khouri, Mei-Ling Chen

University of Graz, Graz, Austria; Baku State University, Baku, Azerbaijan; Federal University of Pernambuco, Recife, Brazil

Keywords: Hepatitis C, antiviral agents, clinical trial, virological response, safety profile, randomized, placebo-controlled

Acute Hepatitis C remains a significant global health challenge, with a need for effective and safe antiviral treatments. The objective of this study was to evaluate the efficacy and safety of a novel...

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2

Global Patterns and Mechanisms of Antimicrobial Resistance in Clinical Isolates: A Multinational Study

Dr. Maria Santana, Dr. Yasmin Al-Hakim, Dr. Niran Chit-pong

Chiang Mai University, Chiang Mai, Thailand; Addis Ababa University, Addis Ababa, Ethiopia; Federal University of Pernambuco, Recife, Brazil

Keywords: antimicrobial resistance, multidrug-resistant strains, horizontal gene transfer, mutation hotspots, genomic sequencing, healthcare practices

Antimicrobial resistance (AMR) poses a significant threat to global health, necessitating a comprehensive understanding of its patterns and underlying mechanisms. This study aimed to investigate the d...

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3

Advancements in Thermodynamic Cycles for Enhanced Energy Efficiency in Power Plants

Mahmoud Aziz, Sakura Nakamura, Juan Carlos Fernandéz

University of Dhaka, Dhaka, Bangladesh; University of Dar es Salaam, Dar es Salaam, Tanzania; Central University of Venezuela, Caracas, Venezuela

Keywords: thermodynamic cycles, energy efficiency, power plants, thermal efficiency, working fluids, emissions reduction

Thermodynamic cycles are fundamental to the operation and efficiency of power plants, which are critical for meeting the global demand for sustainable energy. This study aims to explore innovative mod...

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4

Exploring the Epigenetic Modulation of Gene Expression in Stress Response Mechanisms

Lars Zimmermann, Hiroko Takeda, Amina Safayati

University of Rostock, Rostock, Germany; Kanazawa University, Kanazawa, Japan; Ferdowsi University of Mashhad, Mashhad, Iran

Keywords: epigenetics, gene expression, stress response, DNA methylation, histone modification, non-coding RNAs

Epigenetics plays a crucial role in regulating gene expression in response to environmental stressors. This study aims to unravel the intricate mechanisms through which epigenetic modifications mediat...

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5

Investigating Topological Properties in Non-Hausdorff Spaces Using Constructive Sequence Methods

Arvydas Dargis, Mei-Lin Cheng, Fatima Al-Hashimi

Vilnius University, Vilnius, Lithuania; Makerere University, Kampala, Uganda; University of Antioquia, Medellín, Colombia

Keywords: non-Hausdorff spaces, topological properties, constructive sequences, convergence, continuity, topology

Topology, as a fundamental area of mathematics, has often focused on the study of Hausdorff spaces due to their well-behaved nature. However, non-Hausdorff spaces present intriguing challenges and opp...

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6

Advanced Nonlinear Optical Phenomena in Metamaterials: Theoretical and Experimental Insights

Jan Nowak, Li Wei, Farah Ahmed, Maria Gonzalez

Nicolaus Copernicus University, Toruń, Poland; Lanzhou University, Lanzhou, China; University of Dhaka, Dhaka, Bangladesh

Keywords: metamaterials, nonlinear optics, third-order nonlinear effects, photonic devices, optical Kerr effect, self-focusing

Metamaterials have revolutionized the field of optics by enabling the manipulation of light in unprecedented ways. However, understanding the nonlinear optical properties of these materials is still a...

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7

Exploring the Impact of Adaptive Learning Technologies in Multicultural E-Learning Environments

Bruno Martins, Aisha Khan, Seong-Jin Kim

University of Coimbra, Coimbra, Portugal; Kyungpook National University, Daegu, South Korea; University of Canterbury, Christchurch, New Zealand

Keywords: adaptive learning, multicultural education, e-learning, personalization, engagement, educational technology

E-learning has evolved significantly with the integration of adaptive learning technologies, which cater to diverse learning needs. This study examines the impact of these technologies on student perf...

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8

The Role of Institutional Quality in Economic Development: A Comparative Analysis of Emerging Economies

Ladislav Novák, Aisha Al-Mahmoud, Yu Chen, María Fernanda López

Palacký University, Olomouc, Czech Republic; Yarmouk University, Irbid, Jordan; University of Guadalajara, Guadalajara, Mexico

Keywords: institutional quality, economic development, emerging economies, governance, policy reform, econometric modeling

Economic development in emerging economies hinges significantly on the quality of institutional frameworks. This paper seeks to explore the impact of institutional quality on economic growth across va...

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